— Testing Panel

Regulatory T Cell (Treg)

Regulatory T Cell (Treg) Test Comprehensive Assessment of Regulatory T Cells

Accurately evaluate the quantity and functional status of regulatory T cells, understand immune tolerance and immune balance, assist in predicting disease risk, monitoring treatment response, and evaluating recovery.

Regulatory T Cell (Treg)

Immune Balance Assessment

Evaluate immune balance and risk of immune dysregulation

Precise Data Analysis

Quantify Treg number and functional activity

Disease Risk Prediction

Assess risk of autoimmune diseases, allergies, and tumor-related risks

Personalized Therapy Monitoring

Track treatment response and immune recovery capacity

Key Roles in Immune Balance

Suppress immune overactivation and prevent autoimmunity

Maintain immune tolerance and support normal immune function

Modulate inflammatory responses and reduce tissue damage

Promote immune balance and enhance overall immune quality

Suitable For

Patients with Autoimmune Diseases

Such as rheumatoid arthritis, lupus, psoriasis, thyroiditis, IBD, etc.

Patients with Allergic Conditions

Such as asthma, allergic rhinitis, atopic dermatitis, food allergies, etc.

Patients with Chronic Inflammation

Such as chronic infections, chronic pain, chronic hepatitis, etc.

Health Management and Follow-up

Immune balance evaluation, anti-aging, and disease prevention

Test Contents

Through multiparameter flow cytometry, comprehensively analyze the quantity and function of Treg cells.

Treg Surface Markers

  • CD4+ T Cells
  • CD25 High Expression (IL-2Rα)
  • CD127 Low Expression (IL-7Rα)
  • CD45RA / CD45RO
  • CCR7 · CTLA-4

Treg Functional Markers

  • FoxP3 (Master Transcription Factor)
  • Helios (Stability Marker)
  • Ki-67 (Proliferation Marker)
  • CD39 · CD73 (Suppressive Function)
  • IL-10 · TGF-β (Immunosuppressive Cytokines)

Testing Process

  1. Sample Collection

    Sample Collection

    Collect peripheral blood sample

  2. Cell Isolation

    Cell Isolation

    Isolate peripheral blood mononuclear cells (PBMCs)

  3. Staining

    Staining

    Perform multi-color antibody staining for flow cytometry

  4. AI Analysis

    AI Analysis

    AI algorithm analyzes Treg quantity and function

  5. Report Generation

    Report Generation

    Generate professional analysis report and test results

  6. Clinical Application

    Clinical Application

    Provide personalized health management recommendations

Multiparameter Fluorescence Images (Examples)

CD4 (T Cell)

CD4 (T Cell)

CD25 (IL-2Rα)

CD25 (IL-2Rα)

FoxP3

FoxP3

CD127 (IL-7Rα)

CD127 (IL-7Rα)

Merged Image

Merged Image

Treg Cell Reference Ranges

Treg Indicator Reference Range (%) Clinical Significance
Treg (CD4+CD25+FoxP3+) 5 – 10 Optimal immune balance
CD25 High Expression Treg 3 – 8 Immunosuppressive function indicator
CD127 Low Expression Treg 2 – 6 Stable Treg proportion indicator
Suppressive Function (IL-10+) 1 – 3 Suppressive activity indicator
Proliferation Activity (Ki-67+) 1 – 5 Treg cell activation and proliferation status

* Reference ranges may vary depending on laboratory methods and population characteristics. Please interpret results in combination with clinical conditions.

Clinical Applications

Autoimmune Disease Evaluation

Assess immune tolerance and risk of immune dysregulation

Treatment Efficacy Monitoring

Monitor treatment response and immune balance

Immune Recovery Assessment

Evaluate immune recovery and regeneration

Vaccine Response Prediction

Predict vaccine response and immune effectiveness

Allergy and Inflammation Assessment

Assess allergic and inflammatory responses

Health Management and Anti-aging

Maintain immune balance and support healthy aging

Test Features

  • Multiparameter flow cytometry for precise analysis
  • Quantify Treg number and suppressive function
  • Evaluate immune tolerance and immune balance status
  • AI algorithm analysis to provide health recommendations
  • Monitor treatment response and immune recovery capacity

Test Specifications

  • Sample Type: Peripheral blood, 5–10 mL
  • Test Method: Multiparameter flow cytometry
  • Turnaround Time: 7–10 business days
  • Suitable Age: Adults and children
  • Report Content: Treg quantity, proportion, function, and health recommendations

Notes

  • Fasting is not required
  • Avoid intense exercise 24 hours before testing
  • Inform your doctor of any medications or health conditions
  • If you have an acute infection or fever, it is recommended to postpone the test
  • Test results should be interpreted by a professional physician in combination with clinical findings

FAQ

Q.Is fasting required before the Treg Cell Test?

No. Fasting is not required before the test. However, it is recommended to avoid strenuous exercise and inform your physician about any medications you are currently taking.

Q.What does a low Treg cell count indicate?

A reduced number or function of Treg cells may indicate immune imbalance and may be associated with autoimmune diseases, chronic inflammation, or an increased risk of allergic disorders.

Q.What does a high Treg cell count indicate?

Elevated Treg cell levels may suppress normal immune responses and can be associated with tumor immune evasion, chronic infections, or immunosuppressive conditions. Clinical interpretation is recommended.

Q.What should I do if my test results are abnormal?

Your results should be reviewed by a healthcare professional together with your medical history and clinical findings to develop an appropriate health management or treatment plan.

Q.How often should I repeat the test?

Follow-up testing every 6–12 months is generally recommended. Patients with autoimmune diseases or those receiving immunotherapy may require more frequent monitoring based on physician recommendations.

Q.Are there any risks associated with the test?

The test requires only a small peripheral blood sample and is considered a low-risk procedure similar to a routine blood test.

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